Ozempic face: wat gebeurt er met je huid na gewichtsverlies?

Ozempic face: what happens to your skin after weight loss?

And what can you do about less firm skin, loss of volume, and visible wrinkles?

More and more people are losing weight with the help of GLP-1 medications such as Ozempic, Wegovy, and Mounjaro. In addition to changes in their bodies, some also notice that their faces look different. Their cheeks appear less full, fine lines become more visible, and their skin looks less firm.

These changes are also known as Ozempic face. But what exactly is Ozempic face? Why does your skin change when you lose weight? And what can you do with the right skincare to keep your skin in good condition?

What is Ozempic face?

Ozempic face is not a medical diagnosis, but a popular term for changes in the face after significant or rapid weight loss.

Your face is made up not only of skin, but also of subcutaneous fat tissue that provides volume and support. When you lose weight, this fat tissue often decreases in your face as well.

The result? Your cheeks may look less full, your facial contours may change, and existing wrinkles may become more visible.

Common characteristics of Ozempic face include:

  • Less full or hollowed cheeks.
  • Less firm skin around the jawline.
  • More visible fine lines and wrinkles.
  • A less full facial appearance.
  • Sometimes drier skin.

Although the name suggests otherwise, Ozempic face does not occur exclusively in people who use Ozempic. It can occur with any form of significant weight loss, even without medication.

Why can your skin sag after weight loss?

To understand this, it is important to distinguish between facial volume and skin elasticity.

1. Loss of facial volume

Subcutaneous fat gives the face its naturally full appearance. When this fat tissue decreases, the skin may receive less support. This makes existing folds and wrinkles more visible.

2. Reduced skin elasticity

Collagen and elastin are important proteins that contribute to the firmness and resilience of the skin.

As we get older, the natural production of collagen decreases and the elasticity of the skin changes. As a result, the skin may not adapt as easily to changes in facial volume.

3. Changes in hydration

During weight loss, the moisture balance can also change. Some people eat and drink less, which can make the skin feel drier.

Dry skin often makes fine lines more apparent and can look less supple.

Do GLP-1 medications directly affect your skin?

GLP-1 medications, including semaglutide and tirzepatide, affect appetite and satiety, among other things. This can lead to significant weight loss.

The visible changes we call Ozempic face are primarily associated with the speed and amount of weight loss, rather than exclusively with the medication itself.

Age, genetic predisposition, skin quality, and lifestyle also play a role.

Therefore, not everyone who uses GLP-1 medication will experience a saggy or less full facial skin.

Can Ozempic face be prevented or reversed?

That depends on exactly what changes in the skin.

Lost facial volume cannot be restored with a cream or serum. Skincare cannot replace the underlying fat tissue.

What good skincare can do is support skin quality. Think of intensive hydration, skin barrier care, UV protection, and making fine lines less visible.

Adequate nutrition, protein, hydration, and a responsible pace of weight loss are also important. Always discuss the pace of weight loss and any concerns with your treating physician.

Which ingredients are important after weight loss?

When your skin looks less firm or less full, the focus of your skincare routine should be on three important skin needs.

01: Firm & Smooth

Targeted anti-aging ingredients can help address the visible signs of skin aging.

Prescription Zombie Cell Serum contains 3% ETERWELL® YOUTH, an innovative cosmetic ingredient developed for anti-aging skincare.

The serum is a targeted addition for skin with visible fine lines and reduced elasticity.

02: Hydrate & Plump

Hyaluronic acid is one of the best-known ingredients for intensive hydration.

It helps retain moisture, which can make the skin look fuller, smoother, and more supple. This can make a visible difference, especially with dryness lines.

Prescription Hyaluronic Acid 5% + DMAE 1% combines hydrating care with a formula aimed at a smoother skin appearance.

03: Protect & Restore

A well-cared-for skin barrier helps the skin retain moisture and protects it from external influences.

A moisturizer such as Prescription Edelweiss Cream supports daily skin care.

Sun protection is also essential. UV radiation contributes to collagen breakdown and premature skin aging. Therefore, use a broad-spectrum SPF 30 or higher every morning.

The Prescription Skin Firming Routine

Your weight has changed. Your skin has different needs.

At Prescription Skincare, we do not believe in more products, but in the right products.

That is why we have put together a targeted Skin Firming Routine for caring for the facial skin after weight loss.

The routine consists of five carefully selected products:

01 — CLEANSE

Aloe Vera Cleanser

A gentle cleanser that cleanses the skin without unnecessarily drying it out.

02 — BUILD

Zombie Cell Serum

Targeted anti-aging care for skin with visible signs of aging.

Hyaluronic Acid 5% + DMAE 1%

Intensive hydration for a fuller, smoother, and more supple-looking skin.

03 — MOISTURIZE

Edelweiss Cream

Cares for the skin and supports the skin barrier.

04 — PROTECT

SPF50 Drops

Daily protection against UV radiation that contributes to premature skin aging. Use according to the product instructions and in a sufficient amount for the stated protection.

This routine follows the Prescription philosophy of Cleanse, Peel, Build, Moisturize & Protect. The Peel step is not necessary in this specific routine.

Discover the Sagging Skin Set

When will you see results?

A well-hydrated skin can quickly feel smoother and more supple.

Visible changes in fine lines and skin texture usually take more time. Consistent use for several weeks to months is important, with results varying from person to person and product to product.

Keep in mind that skincare can improve the condition and appearance of your skin, but cannot restore lost facial volume.

Your Skin. Your Prescription.

Whether you have lost weight through lifestyle changes or with the help of GLP-1 medication: your skin may have different needs.

And that is precisely when it is important to understand what your skin needs.

With more than 20 years of experience in professional skincare and insights from more than a million skin treatments, Prescription Skincare helps you put together a personal routine.